Key Takeaways
MedGemma 27B wins:
- Cheaper input tokens
- Cheaper output tokens
GPT-5.3 Codex wins:
- Larger context window
- Faster response time
- Higher intelligence benchmark
- Better at coding
- Supports vision
Price Advantage
MedGemma 27B
Benchmark Advantage
GPT-5.3 Codex
Context Window
GPT-5.3 Codex
Speed
GPT-5.3 Codex
Pricing Comparison
Price Comparison
| Metric | MedGemma 27B | GPT-5.3 Codex | Winner |
|---|---|---|---|
| Input (per 1M tokens) | $0.90 | $1.75 | MedGemma 27B |
| Output (per 1M tokens) | $0.90 | $14.00 | MedGemma 27B |
| Cache Read (per 1M) | $0.45 | $0.17 | GPT-5.3 Codex |
Using a 3:1 input/output ratio, MedGemma 27B is 81% cheaper overall.
MedGemma 27B Providers
No provider data available
GPT-5.3 Codex Providers
No provider data available
Benchmark Comparison
3
Benchmarks Compared
0
MedGemma 27B Wins
0
GPT-5.3 Codex Wins
Benchmark Scores
| Benchmark | MedGemma 27B | GPT-5.3 Codex | Winner |
|---|---|---|---|
Intelligence Index Overall intelligence score | - | 54.0 | - |
Coding Index Code generation & understanding | - | 53.1 | - |
GPQA Graduate-level science | - | 91.5 | - |
GPT-5.3 Codex significantly outperforms in coding benchmarks.
Cost vs Quality
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Y-axis:
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Other models
Context & Performance
Context Window
MedGemma 27B
N/A
tokens
GPT-5.3 Codex
400,000
tokens
Speed Performance
| Metric | MedGemma 27B | GPT-5.3 Codex | Winner |
|---|---|---|---|
| Tokens/second | N/A | 68.3 tok/s | |
| Time to First Token | N/A | 81.66s |
Capabilities
Feature Comparison
| Feature | MedGemma 27B | GPT-5.3 Codex |
|---|---|---|
| Vision (Image Input) | ||
| Tool/Function Calls | ||
| Reasoning Mode | ||
| Audio Input | ||
| Audio Output | ||
| PDF Input | ||
| Prompt Caching | ||
| Web Search |
License & Release
| Property | MedGemma 27B | GPT-5.3 Codex |
|---|---|---|
| License | Proprietary | Proprietary |
| Author | OpenAI | |
| Released | Unknown | Feb 2026 |
MedGemma 27B Modalities
Input
Output
GPT-5.3 Codex Modalities
Input
textimage
Output
text